info@njbiopharmaceuticals.com

675 US Highway 1, Suite B129, North Brunswick, NJ 08902

About Us

COMPANY PROFILE

NJ Biopharmaceuticals LLC is a Contract Research Organization geared towards providing comprehensive chemistry and biology services to biopharmaceutical- and chemical-based technology companies. The company is located in the Commercialization Center for Innovative Technologies (CCIT), a significant biotech incubator in in North Brunswick in the heart of New Jersey’s “Research Corridor” with easy access to New Jersey and New York airports.

While the company has a strong background in synthetic organic chemistry and protein based biopharmaceuticals, it is a “differentiated” service provider with a niche in several areas:

  • Expertise in antibody-drug conjugates (ADCs), bioconjugation to proteins and biomaterials, linker chemistry design for conjugations, ADC constructs, and process development for small molecules and ADCs
  • Expertise in multi-step customized flow chemistry synthetic routes for drug intermediates and APIs along with a unique offering to design custom flow chemistry equipment in collaboration with experts at Amar Equipment Pvt. Ltd.
  • Services to manufacture research-grade protein and antibodies
  • Ability to develop plate-based assays to evaluate the ability of compounds to promote or inhibit cell proliferation

 

COMPANY MISSION

Our mission is to provide value-added chemistry and biopharmaceutical services to enable our clients to accelerate their product development programs and build long-lasting collaborative relationships. Our goal is to provide value through efficient, timely, and cost-effective solutions that meet our clients’ needs. NJ Biopharmaceuticals embraces the standards of teamwork, confidentiality, and reliability with innovative solutions to your most challenging research requirements. Customer satisfaction is our highest priority.

OUR PEOPLE AND CULTURE

We have highly talented and experienced laboratory chemists and biologists with a tremendous passion for chemistry and biology resulting in unique solutions to client programs. Furthermore, our corporate culture is collaborative, communicative, and adaptable.  Most importantly, our scientists strive to deliver quality services in a cost-effective and timely manner.

Our Team

Managing Director: Nareshkumar Jain, Ph.D.

Dr. Jain, Ph.D. is serving as Managing Director of NJ Biopharmaceuticals, LLC. He is also a Non-Executive Chairman of The Platinum Sports Center, LLC (dba Core Volleyball, www.corevball.com) and a member of Robinhood Venture Group located in Philadelphia. He served as Global Head of Chemistry and Senior Vice-President of ADC Biomanufacturing at Abzena plc since December 15, 2015 until January 9, 2017. Dr. Jain founded a chemistry based CRO Company, The Chemistry Research Solution, LLC (TCRS) in 2009 and served as a Managing Director for 6 years. TCRS was acquired by Abzena plc, a UK based biopharmaceutical company in December 2015. Dr. Jain has more than ten years of medicinal chemistry experience at Johnson and Johnson where he worked on advancing new drug molecules from early lead to lead optimization and clinical trials. He has co-authored more than 60 publications, patents, and chapters in medicinal/synthetic chemistry books. Among his notable achievements are the total syntheses of complex natural products including vancomycin and rutamycin. Dr. Jain received his Ph.D. from Boston University, Boston, Massachusetts with Prof. James Panek and was a Post-Doctoral Research Fellow at The Scripps Research Institute, La Jolla, California with Prof. K.C. Nicolaou.

Director of Chemistry and Flow Sciences: Bram Karsten, Ph.D.

Dr. Karsten received his Ph.D. in organic chemistry from Eindhoven University of Technology, where he focused on the synthesis of π-conjugated small molecules and polymers for organic solar cell applications. He performed postdoctoral research at MIT in the group of prof. Buchwald, focusing on the multistep flow synthesis of pharmaceuticals. Outside of academia, Dr. Karsten has held several research positions at small companies, focusing on synthetic chemistry.

Principal Scientist and Head of Biology: Irina Bruck, Ph.D.

Dr. Bruck is a leading protein biochemist with extensive experience in protein characterization, protein chemistry, protein isolation and purification, protein enzymology, and protein immunology.  Dr. Bruck was the first to purify and characterize the UmuD’C polymerase while earning her doctoral degree in the lab of Dr. Myron Goodman.  After earning her Ph.D. at the University of Southern California, Dr. Bruck pursued postdoctoral studies as a Howard Hughes Scholar at Rockefeller University in the lab of Professor of Michael E. O’Donnell, a member of the National Academy of Sciences.  While at Rockefeller, Dr. Bruck was the first to purify intact recombinant protein machinery, composed of more than a dozen molecular subunits, for the replication of DNA from five different Gram-positive bacteria. Dr. Bruck received 5 patents and published 5 first-author manuscripts as the result of this remarkable achievement.  Dr. Bruck then worked as a Research Professor at Vanderbilt University and Florida State University, where she worked to reconstitute eukaryotic replication initiation apparatus using recombinant methods of over 20 budding yeast protein subunits.  Dr. Bruck published 25 manuscripts and received one patent while working as a research professor at Vanderbilt and Florida State.  One of Dr. Bruck’s famous discoveries was that Sld3/Treslin, a replication initiation protein, stimulates kinase phosphorylation and activation of the replication helicase assembly in eukaryotes.  Dr. Bruck is the first-author of the manuscript describing this important discovery, published in the prestigious Proceedings of the National Academy of Sciences, USA.  Dr. Bruck pursued additional studies in immunology at Columbia University College of Medicine prior to beginning her work for NJBiopharmaceuticals.

Head of the General Administration and Finance:   Poonam Amrute

Poonam joined NJ Biopharmaceuticals LLC, as Manager of Finance and General Administration. She ensures smooth functioning of general operations while providing administrative support, accounting, financial reporting, human resources, logistics and communications. Poonam is the first point of contact for the company and functions as the right arm to the Managing Director of the company. She has diverse experience of working for organization across multiple industries. On a personal front, Poonam likes to travel, read and listening to music. She earned her Master’s degree in Accounting and Economics from Pune University, India.

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